Lucifer

First Appearance

Cinderella (1950)

Other Appearances

House of Mouse (2001)
Cinderella II: Dreams Come True (2002)
Cinderella III: A Twist in Time (2007)

Voice

June Foray

Frank Welker

Original Animators

Ward Kimball

Wolfgang Reitherman

John Lounsbery

Norm Ferguson

Stromboli

First Appearance

Pinocchio (1940)

Other Appearances

House of Mouse (2001)

Mickey's House of Villains (2001)

Mickey's Magical Christmas: Snowed In at the House of Mouse (2001)

Origin

Pinocchio (book) by Carlo Collodi

Voice

Charles Judels

Jim Cummings

Original Animator

Bill Tytla

Pluto's Devil

First Appearance

Mickey's Pal Pluto (1933)

Other Appearances

Mickey's Elephant (1936)
Lend a Paw (1941)

Mickey Mouse Works (1999)

House of Mouse (2001)

Voice

Unknown in early shorts

Penn Jillette, 1999-present

The Sheriff of Nottingham

First Appearance

Robin Hood (1973)

Other Appearances

House of Mouse (2001)
Mickey's Magical Christmas: Snowed In at the House of Mouse (2001)

Origin

English folkore

Voice

Pat Buttram

Bill Farmer

Original Animator

Milt Kahl

Adelbert

First Appearance

Mickey's Good Deed (1932)

Captain Gantu

First Appearance

Lilo & Stitch (2002)

Other Appearances

Stitch! The Movie (2003)

Lilo & Stitch: The Series (2003)
Leroy & Stitch (2006)

Stitch! (2008)

Voice

Kevin Michael Richardson

Unshô Ishizuka

Keith Silverstein

Original Animator
Theodore Ty

Duke Igthorn

First Appearance

Adventures of the Gummi Bears (1985)

Voice

Michael Rye

Robbie V.

First Appearance

Gravity Falls (2012)

Voice

T. J. Miller

Pain and Panic

First Appearance

Hercules (1997)

Other Appearances

Hercules TV Series (1998)
Hercules: Zero to Hero (1999)
House of Mouse (2001)

Voices

Pain
Bobcat Goldthwait
Panic
Matt Frewer

Original Animators

Pain
James Lopez

Panic
Brian Ferguson

Both

Allison Renna
Steven K. Thompson
Marc Eoche-Duval

Megavolt

First Appearance

Darkwing Duck (1991)

Voice

Dan Castellaneta

The Prospector, aka Stinky Pete

First Appearance

Toy Story 2 (1999)

Voice

Kelsey Grammer

Lumpjaw

First Appearance

Fun & Fancy Free (1947)

Origin

Little Bear Bongo (children's story) by Sinclair Lewis

Voice

Candy Candido

The Big Bad Wolf

First Appearance

The Three Little Pigs (1933)

Other Appearances

The Big Bad Wolf (1934)

Three Little Wolves (1936)
Mickey's Polo Team (1936)
The Practical Pig (1939)
The Mickey Mouse Club (1955) 
Mickey's Christmas Carol (1983)
 Who Framed Roger Rabbit (1988)
Bonkers (1993)
House of Mouse (2001)

Mickey's House of Villains (2001)

Mickey's Magical Christmas: Snowed In at the House of Mouse (2001)

Origin

Folklore

Voice

Billy Bletcher

Tony Pope

Jim Cummings

Coming Soon!

On February 15, 1925, a character that would become Disney's first major animated villain was introduced in the short Alice Solves the Puzzle. Beginning on February 16, 2014 The Cartoon Character Hall of Fame celebrates with 365 of Disney's animated "rascals, scoundrel, villains, and knaves" ending on February 15, 2015, the 90th anniversary one of Disney's earliest and most prolific ne'er-do-wells.